Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota—A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia?

Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota—A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia?

Colorectal cancer (CRC) and cachexia are associated with the gut microbiota and microbial surface molecules. We characterized the CRC-associated microbiota and investigated whether cachexia affects the microbiota composition. Further, we examined the possible relationship between the microbial surfa...

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Bibliographic Details
Main Authors: Satu Pekkala, Anniina Keskitalo, Emilia Kettunen, Sanna Lensu, Noora Nykänen, Teijo Kuopio, Olli Ritvos, Jaakko Hentilä, Tuuli A. Nissinen, Juha J. Hulmi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
inflammation
activin
myostatin
microbiome
il6
ccl2
mcp-1
Online Access:https://www.mdpi.com/2072-6694/11/11/1799

Internet

https://www.mdpi.com/2072-6694/11/11/1799

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