Post-transcriptional Regulation of PCSK9 by miR-191, miR-222, and miR-224
Since proprotein convertase subtilisin kexin 9 (PCSK9) discovery, a gene involved in LDL metabolism regulation and cardiovascular diseases (CVD), many therapeutic strategies have been introduced for direct targeting of PCSK9. The main goal of these strategies has been to reduce PCSK9 protein level e...
Main Authors: | Parisa Naeli, Fatemeh Mirzadeh Azad, Mahshid Malakootian, Nabil G. Seidah, Seyed J. Mowla |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-11-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fgene.2017.00189/full |
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