Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization

Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization

Bcl-2 family of proteins consists of both pro-apoptotic and anti-apoptotic members that control cellular apoptosis. They predominantly reside in the mitochondria and control the release of apoptotic factors from the mitochondria to the cytosol by regulating its membrane potential and opening the PT...

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Bibliographic Details
Main Authors: Abhinav Grover, Ran Gao, Durai Sundar, Sunil C. Kaul, Renu Wadhwa, Nishant Saxena, Shashank P. Katiyar, Ye Liu
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-10-01
Series:Bioscience Reports
Subjects:
Bcl-2
Bcl-xL
interaction
mortalin
p53 activation
senescence
Online Access:http://www.bioscirep.org/bsr/033/e073/bsr033e073.htm

Internet

http://www.bioscirep.org/bsr/033/e073/bsr033e073.htm

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