Surface Expression of Precursor N-cadherin Promotes Tumor Cell Invasion

The expression of N-cadherin (NCAD) has been shown to correlate with increased tumor cell motility and metastasis. However, NCAD-mediated adhesion is a robust phenomenon and therefore seems to be inconsistent with the “release” from intercellular adhesion required for invasion. We show that in the...

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Bibliographic Details
Main Authors: Deborah Maret, Eugenia Gruzglin, Mohamad Seyed Sadr, Vincent Siu, Weisong Shan, Alexander W. Koch, Nabil G. Seidah, Rolando F. Del Maestro, David R. Colman
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800247