TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells.

The oncotropism of Minute Virus of Mice (MVMp) is partially related to the stimulation of an antiviral response mediated by type-I interferons (IFNs) in normal but not in transformed mouse cells. The present work was undertaken to assess whether the oncotropism displayed against human cells by MVMp...

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Bibliographic Details
Main Authors: Zahari Raykov, Svitlana P Grekova, Rita Hörlein, Barbara Leuchs, Thomas Giese, Nathalia A Giese, Jean Rommelaere, Rainer Zawatzky, Laurent Daeffler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3558501?pdf=render