Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is typically an inefficient and asynchronous process. A variety of technological efforts have been made to accelerate and/or synchronize this process. To define a unified framework to study and compare the dynamics of reprogram...

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Bibliographic Details
Main Authors: Lin L. Liu, Justin Brumbaugh, Ori Bar-Nur, Zachary Smith, Matthias Stadtfeld, Alexander Meissner, Konrad Hochedlinger, Franziska Michor
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Cell Reports
Subjects:
induced pluripotent stem cells
reprogramming
mathematical/probabilistic modeling
birth-death transition processes
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716316540

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http://www.sciencedirect.com/science/article/pii/S2211124716316540

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