The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

A novel variant of the SARS-CoV-2 virus carrying a point mutation in the Spike protein (D614G) has recently emerged and rapidly surpassed others in prevalence. This mutation is in linkage disequilibrium with an ORF1b protein variant (P314L), making it difficult to discern the functional significance...

Full description

Bibliographic Details
Main Authors: Zharko Daniloski, Tristan X Jordan, Juliana K Ilmain, Xinyi Guo, Gira Bhabha, Benjamin R tenOever, Neville E Sanjana
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
COVID-19
SARS-CoV-2
Spike
D614G
coronavirus
Online Access:https://elifesciences.org/articles/65365

Internet

https://elifesciences.org/articles/65365

Similar Items