On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity

On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity

Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL. ANGPTL3, much like ANGPTL4, is a physiologically relevant regulator of LPL activi...

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Bibliographic Details
Main Authors: Oleg Kovrov, Kristian Kølby Kristensen, Erika Larsson, Michael Ploug, Gunilla Olivecrona
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Lipid Research
Subjects:
angiopoietin-like 8
angiopoietin-like 3
angiopoietin-like 4
glycosylphosphatidylinositol-anchored HDL binding protein 1
lipoprotein metabolism
enzymology/enzyme regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032592X

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http://www.sciencedirect.com/science/article/pii/S002222752032592X

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