A combined linkage and exome sequencing analysis for electrocardiogram parameters in the Erasmus Rucphen Family study

A combined linkage and exome sequencing analysis for electrocardiogram parameters in the Erasmus Rucphen Family study

Electrocardiogram (ECG) measurements play a key role in the diagnosis and prediction of cardiac arrhythmias and sudden cardiac death. ECG parameters, such as the PR, QRS, and QT intervals, are known to be heritable and genome-wide association studies (GWAS) of these phenotypes have been successful i...

Full description

Bibliographic Details
Main Authors: Claudia Tamar Silva, Irina Zorkoltseva, Najaf Amin, Ayse Demirkan, Elisabeth Maria van Leeuwen, Jan Kors, Marten van den Berg, Bruno Stricker, André Uitterlinden, Anatoly Kirichenko, Jacqueline C.M. Witteman, Rob Willemsen, Ben Oostra, Tatiana Axenovich, Cornelia Marja Van Duijn, Aaron Isaacs
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Genetics
Subjects:
Electrocardiography
Epidemiology
Genetics
exome sequencing
linkage analysis
Lod Score
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00190/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00190/full

Similar Items