Differential transcript usage in the Parkinson's disease brain.

Studies of differential gene expression have identified several molecular signatures and pathways associated with Parkinson's disease (PD). The role of isoform switches and differential transcript usage (DTU) remains, however, unexplored. Here, we report the first genome-wide study of DTU in PD...

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Bibliographic Details
Main Authors: Fiona Dick, Gonzalo S Nido, Guido Werner Alves, Ole-Bjørn Tysnes, Gry Hilde Nilsen, Christian Dölle, Charalampos Tzoulis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009182