Characterization of the human RFX transcription factor family by regulatory and target gene analysis

Characterization of the human RFX transcription factor family by regulatory and target gene analysis

Abstract Background Evolutionarily conserved RFX transcription factors (TFs) regulate their target genes through a DNA sequence motif called the X-box. Thereby they regulate cellular specialization and terminal differentiation. Here, we provide a comprehensive analysis of all the eight human RFX gen...

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Bibliographic Details
Main Authors: Debora Sugiaman-Trapman, Morana Vitezic, Eeva-Mari Jouhilahti, Anthony Mathelier, Gilbert Lauter, Sougat Misra, Carsten O. Daub, Juha Kere, Peter Swoboda
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
Cell differentiation
Cilia
Spermatogenesis
Immune cell proliferation
Neuronal development
Cell cycle control
Online Access:http://link.springer.com/article/10.1186/s12864-018-4564-6

Internet

http://link.springer.com/article/10.1186/s12864-018-4564-6

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