Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

Integrin-linked kinase (ILK) is a highly evolutionarily conserved, multi-domain signaling protein that localizes to focal adhesions, myofilaments and centrosomes where it forms distinct multi-protein complexes to regulate cell adhesion, cell contraction, actin cytoskeletal organization and mitotic s...

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Bibliographic Details
Main Authors: Mykola Maydan, Paul C McDonald, Jasbinder Sanghera, Jun Yan, Charalampos Rallis, Sheena Pinchin, Gregory E Hannigan, Leonard J Foster, David Ish-Horowicz, Michael P Walsh, Shoukat Dedhar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2932980?pdf=render

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http://europepmc.org/articles/PMC2932980?pdf=render

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