Interplay of Carbonic Anhydrase IX With Amino Acid and Acid/Base Transporters in the Hypoxic Tumor Microenvironment

by Geetha Venkateswaran, Geetha Venkateswaran, Shoukat Dedhar, Shoukat Dedhar, Shoukat Dedhar
Published 2020-11-01

Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX

by Paul C. McDonald, Mridula Swayampakula, Shoukat Dedhar
Published 2018-03-01

A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance

by Edward J. Morris, Jordan A. Gillespie, Christopher A. Maxwell, Shoukat Dedhar
Published 2020-03-01

Integrin-linked kinase regulates interphase and mitotic microtubule dynamics.

by Simin Lim, Eiko Kawamura, Andrew B Fielding, Mykola Maydan, Shoukat Dedhar
Published 2013-01-01

Insulin attenuates apoptosis in neuronal cells by an integrin-linked kinase-dependent mechanism

by Jacqueline Tan, Murat Digicaylioglu, Stacy X.J. Wang, Jonathan Dresselhuis, Shoukat Dedhar, Julia Mills
Published 2019-08-01

Harnessing Induced Essentiality: Targeting Carbonic Anhydrase IX and Angiogenesis Reduces Lung Metastasis of Triple Negative Breast Cancer Xenografts

by Eva-Maria E. Hedlund, Paul C. McDonald, Oksana Nemirovsky, Shannon Awrey, Lasse D.E. Jensen, Shoukat Dedhar
Published 2019-07-01

Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1

by Edward J. Morris, Eiko Kawamura, Jordan A. Gillespie, Aruna Balgi, Nagarajan Kannan, William J. Muller, Michel Roberge, Shoukat Dedhar
Published 2017-05-01

Granulocyte Colony Stimulating Factor Expression in Breast Cancer and Its Association with Carbonic Anhydrase IX and Immune Checkpoints

by Shawn C. Chafe, Nazia Riaz, Samantha Burugu, Dongxia Gao, Samuel C. Y. Leung, Anna F. Lee, Cheng-Han Lee, Shoukat Dedhar, Torsten O. Nielsen
Published 2021-03-01

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

by Mykola Maydan, Paul C McDonald, Jasbinder Sanghera, Jun Yan, Charalampos Rallis, Sheena Pinchin, Gregory E Hannigan, Leonard J Foster, David Ish-Horowicz, Michael P Walsh, Shoukat Dedhar
Published 2010-08-01

Prognostic value of the PrPC-ILK-IDO1 axis in the mesenchymal colorectal cancer subtype

by Alexandre Ghazi, Delphine Le Corre, Camilla Pilati, Julien Taieb, Thomas Aparicio, Audrey Didelot, Shoukat Dedhar, Claire Mulot, Karine Le Malicot, Fatima Djouadi, Aurélien de Reynies, Jean-Marie Launay, Pierre Laurent-Puig, Sophie Mouillet-Richard
Published 2021-01-01

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

by Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar, Claudiu T. Supuran
Published 2020-10-01