The Immunologic Basis for Severe Neonatal Herpes Disease and Potential Strategies for Therapeutic Intervention

by Soren Gantt, William J. Muller
Published 2013-01-01

Herpes Simplex Virus-2 Glycoprotein Interaction with HVEM Influences Virus-Specific Recall Cellular Responses at the Mucosa

by Sarah J. Kopp, Christopher S. Storti, William J. Muller
Published 2012-01-01

The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis

by Douglas R. Wilcox, Stephen S. Folmsbee, William J. Muller, Richard Longnecker
Published 2016-04-01

Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults.

by Douglas R Wilcox, Nitin R Wadhwani, Richard Longnecker, William J Muller
Published 2015-01-01

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

by Bin Xiao, Dongmei Zuo, Alison Hirukawa, Robert D. Cardiff, Richard Lamb, Nahum Sonenberg, William J. Muller
Published 2020-04-01

Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection.

by Miri Yoon, Sarah J Kopp, Joann M Taylor, Christopher S Storti, Patricia G Spear, William J Muller
Published 2011-01-01

Loss of STAT1 from Mouse Mammary Epithelium Results in an Increased Neu-Induced Tumor Burden

by Peter J. Klover, William J. Muller, Gertraud W. Robinson, Ruth M. Pfeiffer, Daisuke Yamaji, Lothar Hennighausen
Published 2010-11-01

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

by Elaine Ngan, Konstantin Stoletov, Harvey W. Smith, Jessica Common, William J. Muller, John D. Lewis, Peter M. Siegel
Published 2017-04-01

Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1

by Edward J. Morris, Eiko Kawamura, Jordan A. Gillespie, Aruna Balgi, Nagarajan Kannan, William J. Muller, Michel Roberge, Shoukat Dedhar
Published 2017-05-01

c-Src regulates cargo transit via the Golgi in pancreatic acinar cells

by Sergiy Kostenko, Chan C. Heu, Jordan R. Yaron, Garima Singh, Cristiane de Oliveira, William J. Muller, Vijay P. Singh
Published 2018-08-01

Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids

by Lyn M. Hillyer, Barbora Hucik, Enzo M. Baracuhy, Zhen Lin, William J. Muller, Lindsay E. Robinson, David W. L. Ma
Published 2020-12-01

Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

by Tung Bui, Jonathan Rennhack, Stephanie Mok, Chen Ling, Marco Perez, Joshua Roccamo, Eran R. Andrechek, Christopher Moraes, William J. Muller
Published 2019-10-01

Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer

by Helen Creedon, Lucy A. Balderstone, Morwenna Muir, Jozef Balla, Laura Gomez-Cuadrado, Natasha Tracey, Joseph Loane, Teresa Klinowska, William J. Muller, Valerie G. Brunton
Published 2016-02-01

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis

by Meghan Morrison Joly, Michelle M. Williams, Donna J. Hicks, Bayley Jones, Violeta Sanchez, Christian D. Young, Dos D. Sarbassov, William J. Muller, Dana Brantley-Sieders, Rebecca S. Cook
Published 2017-06-01

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

by Alison Hirukawa, Harvey W. Smith, Dongmei Zuo, Catherine R. Dufour, Paul Savage, Nicholas Bertos, Radia M. Johnson, Tung Bui, Guillaume Bourque, Mark Basik, Vincent Giguère, Morag Park, William J. Muller
Published 2018-06-01

RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland

by Laura McDonald, Nicola Ferrari, Anne Terry, Margaret Bell, Zahra M. Mohammed, Clare Orange, Alma Jenkins, William J. Muller, Barry A. Gusterson, James C. Neil, Joanne Edwards, Joanna S. Morris, Ewan R. Cameron, Karen Blyth
Published 2014-05-01

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

by Geneviève Deblois, Harvey W. Smith, Ingrid S. Tam, Simon-Pierre Gravel, Maxime Caron, Paul Savage, David P. Labbé, Louis R. Bégin, Michel L. Tremblay, Morag Park, Guillaume Bourque, Julie St-Pierre, William J. Muller, Vincent Giguère
Published 2016-07-01

Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth

by Danielle R. Bond, Richard Kahl, Joshua S. Brzozowski, Helen Jankowski, Crystal Naudin, Mamta Pariyar, Kelly A. Avery-Kiejda, Christopher J. Scarlett, Claude Boucheix, William J. Muller, Leonie K. Ashman, Murray J. Cairns, Séverine Roselli, Judith Weidenhofer
Published 2020-03-01

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

by Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie-Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury, William J. Muller, Morag Park, Philippe P. Roux, Jean-Philippe Gratton, Jean-François Côté
Published 2018-05-01

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

by Alison Hirukawa, Salendra Singh, Jarey Wang, Jonathan P. Rennhack, Matthew Swiatnicki, Virginie Sanguin-Gendreau, Dongmei Zuo, Kamilia Daldoul, Cynthia Lavoie, Morag Park, Eran R. Andrechek, Thomas F. Westbrook, Lyndsay N. Harris, Vinay Varadan, Harvey W. Smith, William J. Muller
Published 2019-10-01