Translational Control in Stem Cells

by Soroush Tahmasebi, Mehdi Amiri, Mehdi Amiri, Nahum Sonenberg, Nahum Sonenberg
Published 2019-01-01

Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3

by Yoshinori Tsukumo, Tommy Alain, Bruno D. Fonseca, Robert Nadon, Nahum Sonenberg
Published 2016-06-01

The translational landscape of ground state pluripotency

by Yaser Atlasi, Seyed Mehdi Jafarnejad, Christos G. Gkogkas, Michiel Vermeulen, Nahum Sonenberg, Hendrik G. Stunnenberg
Published 2020-04-01

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

by Bin Xiao, Dongmei Zuo, Alison Hirukawa, Robert D. Cardiff, Richard Lamb, Nahum Sonenberg, William J. Muller
Published 2020-04-01

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation.

by Yaël Mamane, Emmanuel Petroulakis, Yvan Martineau, Taka-Aki Sato, Ola Larsson, Vinagolu K Rajasekhar, Nahum Sonenberg
Published 2007-01-01

Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.

by Alba Martínez, Marta Sesé, Javier Hernandez Losa, Nathaniel Robichaud, Nahum Sonenberg, Trond Aasen, Santiago Ramón Y Cajal
Published 2015-01-01

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference

by Arti N. Santhanam, Eckart Bindewald, Vinagolu K. Rajasekhar, Ola Larsson, Nahum Sonenberg, Nancy H. Colburn, Bruce A. Shapiro
Published 2009-01-01

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference.

by Arti N. Santhanam, Eckart Bindewald, Vinagolu K. Rajasekhar, Ola Larsson, Nahum Sonenberg, Nancy H. Colburn, Bruce A. Shapiro
Published 2009-01-01

Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference.

by Arti N Santhanam, Eckart Bindewald, Vinagolu K Rajasekhar, Ola Larsson, Nahum Sonenberg, Nancy H Colburn, Bruce A Shapiro
Published 2009-01-01

Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity

by Yumaine Chong, Natasha Saviuk, Brigitte Pie, Nathan Basisty, Ryan K. Quinn, Birgit Schilling, Nahum Sonenberg, Ellis Cooper, A. Pejmun Haghighi
Published 2018-04-01

Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q.

by Yuri V Svitkin, Akiko Yanagiya, Alexey E Karetnikov, Tommy Alain, Marc R Fabian, Arkady Khoutorsky, Sandra Perreault, Ivan Topisirovic, Nahum Sonenberg
Published 2013-01-01

LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction

by Jay Penney, Kazuya Tsurudome, Edward H. Liao, Grant Kauwe, Lindsay Gray, Akiko Yanagiya, Mario R. Calderon, Nahum Sonenberg, A. Pejmun Haghighi
Published 2016-07-01

Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3.

by Marcelo Marcet-Palacios, Brenda Lee Duggan, Irene Shostak, Michele Barry, Tracy Geskes, John A Wilkins, Akiko Yanagiya, Nahum Sonenberg, R Chris Bleackley
Published 2011-12-01

Distinct translational control in CD4+ T cell subsets.

by Eva Bjur, Ola Larsson, Ekaterina Yurchenko, Lei Zheng, Valentina Gandin, Ivan Topisirovic, Shui Li, Carston R Wagner, Nahum Sonenberg, Ciriaco A Piccirillo
Published 2013-05-01

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs

by Aitor Garzia, Seyed Mehdi Jafarnejad, Cindy Meyer, Clément Chapat, Tasos Gogakos, Pavel Morozov, Mehdi Amiri, Maayan Shapiro, Henrik Molina, Thomas Tuschl, Nahum Sonenberg
Published 2017-07-01

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition

by Jennifer E. Dawson, Alaji Bah, Zhenfu Zhang, Robert M. Vernon, Hong Lin, P. Andrew Chong, Manasvi Vanama, Nahum Sonenberg, Claudiu C. Gradinaru, Julie D. Forman-Kay
Published 2020-06-01

4E‐BP1 and 4E‐BP2 double knockout mice are protected from aging‐associated sarcopenia

by Olivier Le Bacquer, Kristell Combe, Véronique Patrac, Brian Ingram, Lydie Combaret, Dominique Dardevet, Christophe Montaurier, Jérôme Salles, Christophe Giraudet, Christelle Guillet, Nahum Sonenberg, Yves Boirie, Stéphane Walrand
Published 2019-06-01

Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

by Hayley I. Muendlein, Joseph Sarhan, Beiyun C. Liu, Wilson M. Connolly, Stephen A. Schworer, Irina Smirnova, Amy Y. Tang, Vladimir Ilyukha, Jodie Pietruska, Soroush Tahmasebi, Nahum Sonenberg, Alexei Degterev, Alexander Poltorak
Published 2020-01-01

eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis

by Hang Ruan, Xiangyun Li, Xiang Xu, Brian J Leibowitz, Jingshan Tong, Lujia Chen, Luoquan Ao, Wei Xing, Jianhua Luo, Yanping Yu, Robert E Schoen, Nahum Sonenberg, Xinghua Lu, Lin Zhang, Jian Yu
Published 2020-11-01

Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing

by Manuel Blandino-Rosano, Rebecca Barbaresso, Margarita Jimenez-Palomares, Nadejda Bozadjieva, Joao Pedro Werneck-de-Castro, Masayuki Hatanaka, Raghavendra G. Mirmira, Nahum Sonenberg, Ming Liu, Markus A. Rüegg, Michael N. Hall, Ernesto Bernal-Mizrachi
Published 2017-07-01