A role for PVRL4-driven cell–cell interactions in tumorigenesis

by Natalya N Pavlova, Christian Pallasch, Andrew EH Elia, Christian J Braun, Thomas F Westbrook, Michael Hemann, Stephen J Elledge
Published 2013-04-01

A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors

by Lior Izhar, Britt Adamson, Alberto Ciccia, Jedd Lewis, Laura Pontano-Vaites, Yumei Leng, Anthony C. Liang, Thomas F. Westbrook, J. Wade Harper, Stephen J. Elledge
Published 2015-06-01

Correction: Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model

by Bhuvanesh Dave, Melissa D. Landis, Lacey E. Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F. Westbrook, Susan G. Hilsenbeck, Dan Liu, Michael T. Lewis, David J. Tweardy, Jenny C. Chang
Published 2012-01-01

Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model.

by Bhuvanesh Dave, Melissa D Landis, David J Tweardy, Jenny C Chang, Lacey E Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F Westbrook, Susan G Hilsenbeck, Dan Liu, Michael T Lewis
Published 2012-01-01

Correction: Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model.

by Bhuvanesh Dave, Melissa D. Landis, Lacey E. Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F. Westbrook, Susan G. Hilsenbeck, Dan Liu, Michael T. Lewis, David J. Tweardy, Jenny C. Chang
Published 2012-01-01

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

by Alison Hirukawa, Salendra Singh, Jarey Wang, Jonathan P. Rennhack, Matthew Swiatnicki, Virginie Sanguin-Gendreau, Dongmei Zuo, Kamilia Daldoul, Cynthia Lavoie, Morag Park, Eran R. Andrechek, Thomas F. Westbrook, Lyndsay N. Harris, Vinay Varadan, Harvey W. Smith, William J. Muller
Published 2019-10-01

TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau

by Maxime WC Rousseaux, Maria de Haro, Cristian A Lasagna-Reeves, Antonia De Maio, Jeehye Park, Paymaan Jafar-Nejad, Ismael Al-Ramahi, Ajay Sharma, Lauren See, Nan Lu, Luis Vilanova-Velez, Tiemo J Klisch, Thomas F Westbrook, Juan C Troncoso, Juan Botas, Huda Y Zoghbi
Published 2016-10-01

Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression

by Cody T. Mowery, Jaime M. Reyes, Lucia Cabal-Hierro, Kelly J. Higby, Kristen L. Karlin, Jarey H. Wang, Robert J. Kimmerling, Paloma Cejas, Klothilda Lim, Hubo Li, Takashi Furusawa, Henry W. Long, David Pellman, Bjoern Chapuy, Michael Bustin, Scott R. Manalis, Thomas F. Westbrook, Charles Y. Lin, Andrew A. Lane
Published 2018-11-01

The Oncogenic STP Axis Promotes Triple-Negative Breast Cancer via Degradation of the REST Tumor Suppressor

by Kristen L. Karlin, Gourish Mondal, Jessica K. Hartman, Siddhartha Tyagi, Sarah J. Kurley, Chris S. Bland, Tiffany Y.T. Hsu, Alexander Renwick, Justin E. Fang, Ilenia Migliaccio, Celetta Callaway, Amritha Nair, Rocio Dominguez-Vidana, Don X. Nguyen, C. Kent Osborne, Rachel Schiff, Li-Yuan Yu-Lee, Sung Y. Jung, Dean P. Edwards, Susan G. Hilsenbeck, Jeffrey M. Rosen, Xiang H.-F. Zhang, Chad A. Shaw, Fergus J. Couch, Thomas F. Westbrook
Published 2014-11-01