Impact of time-varying cumulative bevacizumab exposures on survival: re-analysis of data from randomized clinical trial in patients with metastatic colo-rectal cancer

by Adrien Guilloteau, Michal Abrahamowicz, Olayide Boussari, Valérie Jooste, Thomas Aparicio, Catherine Quantin, Karine Le Malicot, Christine Binquet
Published 2021-01-01

Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment

by Tristan Courau, Julie Bonnereau, Justine Chicoteau, Hugo Bottois, Romain Remark, Laura Assante Miranda, Antoine Toubert, Mathieu Blery, Thomas Aparicio, Matthieu Allez, Lionel Le Bourhis
Published 2019-03-01

UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

by Esther Aguilar, Pauline Esteves, Tiphaine Sancerni, Véronique Lenoir, Thomas Aparicio, Frédéric Bouillaud, Renaud Dentin, Carina Prip-Buus, Daniel Ricquier, Claire Pecqueur, Sandra Guilmeau, Marie-Clotilde Alves-Guerra
Published 2019-08-01

Surgical and regional treatments for colorectal cancer metastases in older patients: A systematic review and meta-analysis.

by Nicola de'Angelis, Capucine Baldini, Raffaele Brustia, Patrick Pessaux, Daniele Sommacale, Alexis Laurent, Bertrand Le Roy, Vania Tacher, Hicham Kobeiter, Alain Luciani, Elena Paillaud, Thomas Aparicio, Florence Canuï-Poitrine, Evelyne Liuu
Published 2020-01-01

Comparison of three lymph node staging schemes for predicting the outcome in patients with small bowel adenocarcinoma: A population-based cohort and international multicentre cohor...

by Yang-Yang Zhou, Xiao-Jing Du, Chi-Hao Zhang, Thomas Aparicio, Aziz Zaanan, Pauline Afchain, Li-Ping Chen, Sun-Kuan Hu, Pei-Chen Zhang, Ming Wu, Qing-Wei Zhang, Hong Wang
Published 2019-03-01

Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease.

by Magali Fasseu, Xavier Tréton, Cécile Guichard, Eric Pedruzzi, Dominique Cazals-Hatem, Christophe Richard, Thomas Aparicio, Fanny Daniel, Jean-Claude Soulé, Richard Moreau, Yoram Bouhnik, Marc Laburthe, André Groyer, Eric Ogier-Denis
Published 2010-01-01

Prognostic value of the PrPC-ILK-IDO1 axis in the mesenchymal colorectal cancer subtype

by Alexandre Ghazi, Delphine Le Corre, Camilla Pilati, Julien Taieb, Thomas Aparicio, Audrey Didelot, Shoukat Dedhar, Claire Mulot, Karine Le Malicot, Fatima Djouadi, Aurélien de Reynies, Jean-Marie Launay, Pierre Laurent-Puig, Sophie Mouillet-Richard
Published 2021-01-01

Personalized four-category staging for predicting prognosis in patients with small bowel Adenocarcinoma: an international development and validation study

by Zi-Hao Dai, Qi-Wen Wang, Qing-Wei Zhang, Xia-Lin Yan, Thomas Aparicio, Yang-Yang Zhou, Huan Wang, Chi-Hao Zhang, Aziz Zaanan, Pauline Afchain, Yan Zhang, Hui-Min Chen, Yun-Jie Gao, Zhi-Zheng Ge
Published 2020-10-01

Efficacy and safety of pasireotide-LAR for the treatment of refractory bleeding due to gastrointestinal angiodysplasias: results of the ANGIOPAS multicenter phase II noncomparative...

by Robert Benamouzig, Mourad Benallaoua, Jean-Christophe Saurin, Marouane Boubaya, Christophe Cellier, René Laugier, Magalie Vincent, Christian Boustière, Rodica Gincul, Elia Samaha, Philippe Grandval, Thomas Aparicio, Gheorghe Airinei, Bakhtiar Bejou, Cyriaque Bon, Jean-Jacques Raynaud, Vincent Levy, Denis Sautereau
Published 2018-02-01

Impact on health‐related quality of life deterioration‐free survival of a first‐line therapy combining nab‐paclitaxel plus either gemcitabine or simplified leucovorin and fluoroura...

by Emilie Charton, Jean‐Baptiste Bachet, Pascal Hammel, Jérôme Desramé, Benoist Chibaudel, Romain Cohen, Philippe Debourdeau, Jérome Dauba, Thierry Lecomte, Jean‐François Seitz, Christophe Tournigand, Thomas Aparicio, Véronique Guerin‐Meyer, Julien Taieb, Julien Volet, Christophe Louvet, Amélie Anota, Franck Bonnetain
Published 2019-09-01

EPIGIST: An observational real-life study on patients with metastatic gastrointestinal stromal tumors receiving imatinib.

by Olivier Bouché, Axel Le Cesne, Maria Rios, Loic Chaigneau, Antoine Italiano, Florence Duffaud, Thierry Lecomte, Dominique Arsène, Sylvain Manfredi, Thomas Aparicio, Stéphane Remy, Nicolas Isambert, Olivier Collard, Frank Priou, François Bertucci, Roland Sambuc, Ségolene Bisot-Locard, Olivier Bourges, Sylvie Chabaud, Jean-Yves Blay
Published 2018-01-01

Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

by Julie Niogret, Emeric Limagne, Marion Thibaudin, Julie Blanc, Aurelie Bertaut, Karine Le Malicot, Yves Rinaldi, François-Xavier Caroli-Bosc, Franck Audemar, Suzanne Nguyen, Corinne Sarda, Catherine Lombard-Bohas, Christophe Locher, Miguel Carreiro, Jean-Louis Legoux, Pierre-Luc Etienne, Mathieu Baconnier, Marc Porneuf, Thomas Aparicio, Francois Ghiringhelli
Published 2020-05-01

<em>BRAF</em> Mutation Status in Circulating Tumor DNA from Patients with Metastatic Colorectal Cancer: Extended Mutation Analysis from the AGEO RASANC Study

by Leo Mas, Jean-Baptiste Bachet, Valerie Taly, Olivier Bouché, Julien Taieb, Romain Cohen, Aurelia Meurisse, Corinne Normand, Jean-Marc Gornet, Pascal Artru, Samy Louafi, Anne Thirot-Bidault, Isabelle Baumgaertner, Romain Coriat, David Tougeron, Thierry Lecomte, Florence Mary, Thomas Aparicio, Lysiane Marthey, Helene Blons, Dewi Vernerey, Pierre Laurent-Puig
Published 2019-07-01

MRI-Based Radiomics Input for Prediction of 2-Year Disease Recurrence in Anal Squamous Cell Carcinoma

by Nicolas Giraud, Olivier Saut, Thomas Aparicio, Philippe Ronchin, Louis-Arnaud Bazire, Emilie Barbier, Claire Lemanski, Xavier Mirabel, Pierre-Luc Etienne, Astrid Lièvre, Wulfran Cacheux, Ariane Darut-Jouve, Christelle De la Fouchardière, Arnaud Hocquelet, Hervé Trillaud, Thomas Charleux, Gilles Breysacher, Delphine Argo-Leignel, Alexandre Tessier, Nicolas Magné, Meher Ben Abdelghani, Côme Lepage, Véronique Vendrely
Published 2021-01-01

The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancerResearch in context

by Delphine Le Corre, Alexandre Ghazi, Ralyath Balogoun, Camilla Pilati, Thomas Aparicio, Séverine Martin-Lannerée, Laetitia Marisa, Fatima Djouadi, Virginie Poindessous, Carole Crozet, Jean-François Emile, Claire Mulot, Karine Le Malicot, Valérie Boige, Hélène Blons, Aurélien de Reynies, Julien Taieb, François Ghiringhelli, Jaafar Bennouna, Jean-Marie Launay, Pierre Laurent-Puig, Sophie Mouillet-Richard
Published 2019-08-01

Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of Frenc...

by Stefano Kim, Marine Jary, Thierry André, Véronique Vendrely, Bruno Buecher, Eric François, François-Clément Bidard, Sarah Dumont, Emmanuelle Samalin, Didier Peiffert, Simon Pernot, Nabil Baba-Hamed, Farid El Hajbi, Olivier Bouché, Jérôme Desrame, Aurélie Parzy, Mustapha Zoubir, Christophe Louvet, Jean-Baptiste Bachet, Thierry Nguyen, Meher Ben Abdelghani, Denis Smith, Christelle De La Fouchardière, Thomas Aparicio, Jaafar Bennouna, Jean-Marc Gornet, Marion Jacquin, Franck Bonnetain, Christophe Borg
Published 2017-08-01