Transcriptional profiling predicts running promotes cerebrovascular remodeling in young but not midlife mice

Abstract Background The incidence of dementia and cognitive decline is increasing with no therapy or cure. One of the reasons treatment remains elusive is because there are various pathologies that contribute to age-related cognitive decline. Specifically, with Alzheimer’s disease, targeting to redu...

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Bibliographic Details
Main Authors: Kate E. Foley, Hongtian Stanley Yang, Leah C. Graham, Gareth R. Howell
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-6230-z