Neuropathological responses to chronic NMDA in rats are worsened by dietary n-3 PUFA deprivation but are not ameliorated by fish oil supplementation.

Dietary long-chain n-3 polyunsaturated fatty acid (PUFA) supplementation may be beneficial for chronic brain illnesses, but the issue is not agreed on. We examined effects of dietary n-3 PUFA deprivation or supplementation, compared with an n-3 PUFA adequate diet (containing alpha-linolenic acid [18...

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Bibliographic Details
Main Authors: Vasken L Keleshian, Matthew Kellom, Hyung-Wook Kim, Ameer Y Taha, Yewon Cheon, Miki Igarashi, Stanley I Rapoport, Jagadeesh S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4010416?pdf=render