The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine

The effectiveness of methylene blue (MB) combined with pyrimethamine (PYR), chloroquine (CQ) or quinine (Q) was examined in a classical four-day suppressive test against a causative agent of rodent malaria, Plasmodium berghei. A marked potentiation was observed when MB was administered at a non-cura...

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Bibliographic Details
Main Authors: Giovanny Garavito, Stéphane Bertani, Miguel Quiliano, Alexis Valentin, Ignacio Aldana, Eric Deharo
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000600019&lng=en&tlng=en