Temporal dynamics of intradermal cytokine response to tuberculin in Mycobacterium bovis BCG-vaccinated cattle using sampling microneedles

Abstract Bovine tuberculosis (bTB) is a disease of livestock with severe and worldwide economic, animal welfare and zoonotic consequences. Application of test-and-slaughter-based control polices reliant on tuberculin skin testing has been the mainstay of bTB control in cattle. However, little is kno...

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Bibliographic Details
Main Authors: Sabine Steinbach, Sasan Jalili-Firoozinezhad, Sreenidhi Srinivasan, Mariane B. Melo, Sonya Middleton, Timm Konold, Michael Coad, Paula T. Hammond, Darrell J. Irvine, Martin Vordermeier, Vivek Kapur
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86398-6