Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha

Background: Peroxisome proliferator-activated receptor alpha (PPARA) is a major regulator of fatty acid oxidation and severe hepatic steatosis occurs during acute fasting in Ppara-null mice. Thus, PPARA is considered an important mediator of the fasting response; however, its role in other fasting r...

Full description

Bibliographic Details
Main Authors: Guolin Li, Chad N. Brocker, Tingting Yan, Cen Xie, Kristopher W. Krausz, Rong Xiang, Frank J. Gonzalez
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817306440