Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis[S]

by Fei Li, Andrew D. Patterson, Kristopher W. Krausz, Naoki Tanaka, Frank J. Gonzalez
Published 2012-08-01

Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra sphenanthera Extract) against Acute Acetaminophen Toxicity

by Huichang Bi, Fei Li, Kristopher W. Krausz, Aijuan Qu, Caroline H. Johnson, Frank J. Gonzalez
Published 2013-01-01

Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice.

by Daxesh P Patel, Kristopher W Krausz, Cen Xie, Diren Beyoğlu, Frank J Gonzalez, Jeffrey R Idle
Published 2017-01-01

Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha

by Guolin Li, Chad N. Brocker, Tingting Yan, Cen Xie, Kristopher W. Krausz, Rong Xiang, Frank J. Gonzalez
Published 2018-01-01

Corrigendum to “Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha” [Mol Metab 7 (2018) 80–89]

by Guolin Li, Chad N. Brocker, Tingting Yan, Cen Xie, Kristopher W. Krausz, Rong Xiang, Frank J. Gonzalez
Published 2018-03-01

Metabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolism.

by Eric D Ciappio, Kristopher W Krausz, Mark Rochman, Takashi Furusawa, Jessica A Bonzo, Lino Tessarollo, Frank J Gonzalez, Michael Bustin
Published 2014-01-01

Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier.

by Luis F Menezes, Fang Zhou, Andrew D Patterson, Klaus B Piontek, Kristopher W Krausz, Frank J Gonzalez, Gregory G Germino
Published 2012-01-01

Intestinal CYP3A4 protects against lithocholic acid-induced hepatotoxicity in intestine-specific VDR-deficient mice[S]

by Jie Cheng, Zhong-Ze Fang, Jung-Hwan Kim, Kristopher W. Krausz, Naoki Tanaka, JohnY.L. Chiang, Frank J. Gonzalez
Published 2014-03-01

Global Metabolomics Reveals Urinary Biomarkers of Breast Cancer in a MCF-7 Xenograft Mouse Model

by Frank J. Gonzalez, Melinda G. Hollingshead, Kristopher W. Krausz, Raymond D. Divelbiss, Jessica A. Bonzo, Soumen K. Manna, Caroline H. Johnson
Published 2013-08-01

Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge

by Joo-Youn Cho, Tsutomu Matsubara, Dong Wook Kang, Sung-Hoon Ahn, Kristopher W. Krausz, Jeffrey R. Idle, Hans Luecke, Frank J. Gonzalez
Published 2010-05-01

Disruption of tumor suppressor gene Hint1 leads to remodeling of the lipid metabolic phenotype of mouse liver[S]

by Diren Beyoğlu, Kristopher W. Krausz, Juliette Martin, Olivier Maurhofer, Juliane Dorow, Uta Ceglarek, Frank J. Gonzalez, Jean-François Dufour, Jeffrey R. Idle
Published 2014-11-01

Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation

by Joo-Youn Cho, Dong Wook Kang, Xiaochao Ma, Sung-Hoon Ahn, Kristopher W. Krausz, Hans Luecke, Jeffrey R. Idle, Frank J. Gonzalez
Published 2009-05-01

Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice

by Chad N. Brocker, Daxesh P. Patel, Thomas J. Velenosi, Donghwan Kim, Tingting Yan, Jiang Yue, Guolin Li, Kristopher W. Krausz, Frank J. Gonzalez
Published 2018-11-01

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans[S]

by Shogo Takahashi, Tatsuki Fukami, Yusuke Masuo, Chad N. Brocker, Cen Xie, Kristopher W. Krausz, C. Roland Wolf, Colin J. Henderson, Frank J. Gonzalez
Published 2016-12-01

Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development

by Shogo Takahashi, Naoki Tanaka, Tatsuki Fukami, Cen Xie, Tomoki Yagai, Donghwan Kim, Thomas J. Velenosi, Tingting Yan, Kristopher W. Krausz, Moshe Levi, Frank J. Gonzalez
Published 2018-12-01

TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury[S]

by Tsutomu Matsubara, Naoki Tanaka, Misako Sato, Dong Wook Kang, Kristopher W. Krausz, Kathleen C. Flanders, Kazuo Ikeda, Hans Luecke, Lalage M. Wakefield, Frank J. Gonzalez
Published 2012-12-01

Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites

by Chad N. Brocker, Thomas Velenosi, Hania K. Flaten, Glenn McWilliams, Kyle McDaniel, Shelby K. Shelton, Jessica Saben, Kristopher W. Krausz, Frank J. Gonzalez, Andrew A. Monte
Published 2020-03-01

Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α

by Yusuke Inoue, Ai-Ming Yu, Sun Hee Yim, Xiaochao Ma, Kristopher W. Krausz, Junko Inoue, Charlie C. Xiang, Michael J. Brownstein, Gösta Eggertsen, Ingemar Björkhem, Frank J. Gonzalez
Published 2006-01-01

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

by Jung-Hwan Kim, Tsutomu Matsubara, Jaekwon Lee, Cristina Fenollar-Ferrer, Kyungreem Han, Donghwan Kim, Shang Jia, Christopher J. Chang, Heejung Yang, Tomokazu Nagano, Kristopher W. Krausz, Sun-Hee Yim, Frank J. Gonzalez
Published 2021-01-01

A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders[S]

by Zhong-Ze Fang, Rong-Rong He, Yun-Feng Cao, Naoki Tanaka, Changtao Jiang, Kristopher W. Krausz, Yunpeng Qi, Pei-Pei Dong, Chun-Zhi Ai, Xiao-Yu Sun, Mo Hong, Guang-Bo Ge, Frank J. Gonzalez, Xiao-Chi Ma, Hong-Zhi Sun
Published 2013-12-01