Advanced knowledge in drug metabolism and pharmacokinetics

by Ai-Ming Yu
Published 2016-09-01

MicroRNAs in non‐small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential

by Hannah Petrek, Ai‐Ming Yu
Published 2019-12-01

Noncoding microRNAs: small RNAs play a big role in regulation of ADME?

by Ai-Ming Yu, Yu-Zhuo Pan
Published 2012-04-01

The HMOX1 Pathway as a Promising Target for the Treatment and Prevention of SARS-CoV-2 of 2019 (COVID-19)

by Neelu Batra, Cristabelle De Souza, Jyoti Batra, Alan G. Raetz, Ai-Ming Yu
Published 2020-09-01

Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice

by Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager, Stephan Schmidt, Ai-Ming Yu
Published 2016-09-01

Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression

by Xin Li, Ye Tian, Mei-Juan Tu, Pui Yan Ho, Neelu Batra, Ai-Ming Yu
Published 2019-05-01

A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma.

by Fernando Alegre, Amanda R Ormonde, Kellie M Snider, Kevin Woolard, Ai-Ming Yu, Luke A Wittenburg
Published 2018-01-01

Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

by Wanrong Yi, Mei-Juan Tu, Zhenzhen Liu, Chao Zhang, Neelu Batra, Ai-Xi Yu, Ai-Ming Yu
Published 2020-01-01

Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity

by Joseph L. Jilek, Qian-Yu Zhang, Mei-Juan Tu, Pui Yan Ho, Zhijian Duan, Jing-Xin Qiu, Ai-Ming Yu
Published 2019-03-01

Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling

by Xiong Zhang, Zenghong Huang, Junjian Wang, Zhao Ma, Joy Yang, Eva Corey, Christopher P. Evans, Ai-Ming Yu, Hong-Wu Chen
Published 2021-04-01

Novel Synergistic Combination of Mitotic Arrest and Promotion of Apoptosis for Treatment of Pancreatic Adenocarcinoma

by Zhijian Duan, Danielle Chinn, Mei-Juan Tu, Qian-Yu Zhang, Jasmine Huynh, Justin Chen, Philip Mack, Ai-Ming Yu, Edward J. Kim
Published 2019-04-01

Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress

by Tao Yu, Yong-Tao Wang, Pan Chen, Yu-Hua Li, Yi-Xin Chen, Hang Zeng, Ai-Ming Yu, Min Huang, Hui-Chang Bi
Published 2015-01-01

Current trends in drug metabolism and pharmacokinetics

by Yuhua Li, Qiang Meng, Mengbi Yang, Dongyang Liu, Xiangyu Hou, Lan Tang, Xin Wang, Yuanfeng Lyu, Xiaoyan Chen, Kexin Liu, Ai-Ming Yu, Zhong Zuo, Huichang Bi
Published 2019-11-01

Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α

by Yusuke Inoue, Ai-Ming Yu, Sun Hee Yim, Xiaochao Ma, Kristopher W. Krausz, Junko Inoue, Charlie C. Xiang, Michael J. Brownstein, Gösta Eggertsen, Ingemar Björkhem, Frank J. Gonzalez
Published 2006-01-01

The Optimal Outcome of Suppressing Ewing Sarcoma Growth in vivo With Biocompatible Bioengineered miR-34a-5p Prodrug

by Dai-Feng Li, Dai-Feng Li, Ying Yuan, Mei-Juan Tu, Xiang Hu, Yi-Zhou Li, Wan-Rong Yi, Peng-Cheng Li, Yong Zhao, Zhen Cheng, Ai-Ming Yu, Chao Jian, Ai-Xi Yu
Published 2020-02-01

Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium...

by Ai-Ming Yu, Magnus Ingelman-Sundberg, Nathan J. Cherrington, Lauren M. Aleksunes, Ulrich M. Zanger, Wen Xie, Hyunyoung Jeong, Edward M. Morgan, Peter J. Turnbaugh, Curtis D. Klaassen, Aadra P. Bhatt, Matthew R. Redinbo, Pengying Hao, David J. Waxman, Li Wang, Xiao-bo Zhong
Published 2017-03-01