Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

Summary: The elicitation of autologous neutralizing responses by immunization with HIV-1 envelope (Env) trimers conformationally stabilized in a prefusion closed state has generated considerable interest in the HIV-1 vaccine field. However, soluble prefusion closed Env trimers have been produced fro...

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Bibliographic Details
Main Authors: M. Gordon Joyce, Ivelin S. Georgiev, Yongping Yang, Aliaksandr Druz, Hui Geng, Gwo-Yu Chuang, Young Do Kwon, Marie Pancera, Reda Rawi, Mallika Sastry, Guillaume B.E. Stewart-Jones, Angela Zheng, Tongqing Zhou, Misook Choe, Joseph G. Van Galen, Rita E. Chen, Christopher R. Lees, Sandeep Narpala, Michael Chambers, Yaroslav Tsybovsky, Ulrich Baxa, Adrian B. McDermott, John R. Mascola, Peter D. Kwong
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717316364

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http://www.sciencedirect.com/science/article/pii/S2211124717316364

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