The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte. Pathogenic Histoplasma yeast cells, but not avirulent mycelial cell...

Full description

Bibliographic Details
Main Authors: Andrew L. Garfoot, Qian Shen, Marcel Wuthrich, Bruce S. Klein, Chad A. Rappleye
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e01388-15