Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors
Targeted therapies for solid tumors in children, adolescents, and young adults (C-AYA) lag behind that of adult carcinomas. Here, the authors study the germline genomic signatures of 1,507 C-AYA patients with solid tumors and find pathogenic/likely pathogenic germline variants in diverse genes of wh...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16067-1 |