Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance

Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance

Male breast cancer (MBC) is a rare and understudied disease compared with female BC. About 15% of MBCs are associated with germline mutation in BC susceptibility genes, mainly <i>BRCA1/2</i> and <i>PALB2</i>. Hereditary MBCs are likely to represent a subgroup of tumors with a...

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Bibliographic Details
Main Authors: Veronica Zelli, Valentina Silvestri, Virginia Valentini, Agostino Bucalo, Piera Rizzolo, Ines Zanna, Simonetta Bianchi, Anna Coppa, Giuseppe Giannini, Laura Cortesi, Daniele Calistri, Maria Grazia Tibiletti, Stephen B. Fox, kCon Fab, Domenico Palli, Laura Ottini
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
male breast cancer
transcriptome profiling
germline mutations
<i>BRCA1/2</i>
molecular subtypes
Online Access:https://www.mdpi.com/2072-6694/13/18/4515

Internet

https://www.mdpi.com/2072-6694/13/18/4515

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