An efficient partial synthesis of 4′-O-methylquercetin via regioselective protection and alkylation of quercetin

An efficient partial 5-step synthesis of 4′-O-methylquercetin from quercetin in 63% yield is reported. This strategy relies on the selective protection of the catechol group with dichlorodiphenylmethane in diphenyl ether as solvent and on the selective protection of the hydroxyl groups at positions...

Full description

Bibliographic Details
Main Authors: Nian-Guang Li, Zhi-Hao Shi, Yu-Ping Tang, Jian-Ping Yang, Jin-Ao Duan
Format: Article
Language:English
Published: Beilstein-Institut 2009-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.5.60