ST2 Requires Th2-, but Not Th17-, Type Airway Inflammation in Epicutaneously Antigen-Sensitized Mice

ST2 Requires Th2-, but Not Th17-, Type Airway Inflammation in Epicutaneously Antigen-Sensitized Mice

Background: IL-33 is known to induce Th2-type cytokine production by various types of cells through its receptors, ST2 and IL-1RAcP. Polymorphism in the ST2 and/or IL-33 genes was found in patients with atopic dermatitis and asthma, implying that the IL-33/ST2 pathway is closely associated with susc...

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Bibliographic Details
Main Authors: Hideaki Morita, Ken Arae, Tatsukuni Ohno, Naoki Kajiwara, Keisuke Oboki, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Kenji Matsumoto, Susumu Nakae
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Allergology International
Subjects:
asthma
eosinophils
epicutaneous sensitization
IL-33
ST2
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015302203

Internet

http://www.sciencedirect.com/science/article/pii/S1323893015302203

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