Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
To advance our understanding of pathological features associated with Alzheimer’s disease (AD), chemical tools with distinct specificity towards AD targets would be valuable. Here the authors used a structure-mechanism-based design strategy to obtain small molecules as chemical regulators for distin...
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Bibliographic Details
Main Authors: |
Michael W. Beck,
Jeffrey S. Derrick,
Richard A. Kerr,
Shin Bi Oh,
Woo Jong Cho,
Shin Jung C. Lee,
Yonghwan Ji,
Jiyeon Han,
Zahra Aliakbar Tehrani,
Nayoung Suh,
Sujeong Kim,
Scott D. Larsen,
Kwang S. Kim,
Joo-Yong Lee,
Brandon T. Ruotolo,
Mi Hee Lim |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2016-10-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/ncomms13115
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