Nanobody mediated crystallization of an archeal mechanosensitive channel.

Mechanosensitive channels (MS) are integral membrane proteins and allow bacteria to survive sudden changes in external osmolarity due to transient opening of their pores. The efflux of cytoplasmic osmolytes reduces the membrane tension and prevents membrane rupture. Therefore these channels serve as...

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Bibliographic Details
Main Authors: Christian Löw, Yin Hoe Yau, Els Pardon, Caroline Jegerschöld, Lisa Wåhlin, Esben M Quistgaard, Per Moberg, Susana Geifman-Shochat, Jan Steyaert, Pär Nordlund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804602?pdf=render