Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

Abstract Introduction This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods MSC-derived extracellular vesicles from old and young rat bone marrows were isolated by ultracentrifu...

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Main Authors: Juan Fafián-Labora, Miriam Morente-López, María José Sánchez-Dopico, Onno J. Arntz, Fons A. J. van de Loo, Javier De Toro, María C. Arufe
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-019-1534-0