Accurate prediction of DnaK-peptide binding via homology modelling and experimental data.

Molecular chaperones are essential elements of the protein quality control machinery that governs translocation and folding of nascent polypeptides, refolding and degradation of misfolded proteins, and activation of a wide range of client proteins. The prokaryotic heat-shock protein DnaK is the E. c...

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Bibliographic Details
Main Authors: Joost Van Durme, Sebastian Maurer-Stroh, Rodrigo Gallardo, Hannah Wilkinson, Frederic Rousseau, Joost Schymkowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2717214?pdf=render