Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis.

Interleukin-6 (IL-6) is a pleiotropic cytokine that affects various functions, including tumor development. Although the importance of IL-6 in gastric cancer has been documented in experimental and clinical studies, the mechanism by which IL-6 promotes gastric cancer remains unclear. In this study,...

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Main Authors: Hiroto Kinoshita, Yoshihiro Hirata, Hayato Nakagawa, Kei Sakamoto, Yoku Hayakawa, Ryota Takahashi, Wachiko Nakata, Kosuke Sakitani, Takako Serizawa, Yohko Hikiba, Masao Akanuma, Wataru Shibata, Shin Maeda, Kazuhiko Koike
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3625204?pdf=render