Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program.

Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program.

<h4>Background</h4>Mitochondria support critical cellular functions, such as energy production through oxidative phosphorylation, regulation of reactive oxygen species, apoptosis, and calcium homeostasis.<h4>Objective</h4>Given the heightened level of cellular activity in pat...

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Bibliographic Details
Main Authors: Maxwell P Cocco, Evan White, Shujie Xiao, Donglei Hu, Angel Mak, Patrick Sleiman, Mao Yang, Kevin R Bobbitt, Hongsheng Gui, Albert M Levin, Samantha Hochstadt, Kyle Whitehouse, Dean Rynkowski, Andrea J Barczak, Gonçalo Abecasis, Thomas W Blackwell, Hyun Min Kang, Deborah A Nickerson, Soren Germer, Jun Ding, David E Lanfear, Frank Gilliland, W James Gauderman, Rajesh Kumar, David J Erle, Fernando Martinez, Hakon Hakonarson, Esteban G Burchard, L Keoki Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242364

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https://doi.org/10.1371/journal.pone.0242364

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