Citrullination of HP1γ chromodomain affects association with chromatin

Abstract Background Stem cell differentiation involves major chromatin reorganisation, heterochromatin formation and genomic relocalisation of structural proteins, including heterochromatin protein 1 gamma (HP1γ). As the principal reader of the repressive histone marks H3K9me2/3, HP1 plays a key rol...

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Bibliographic Details
Main Authors: Meike Wiese, Andrew J. Bannister, Srinjan Basu, Wayne Boucher, Kai Wohlfahrt, Maria A. Christophorou, Michael L. Nielsen, David Klenerman, Ernest D. Laue, Tony Kouzarides
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-019-0265-x