RefShannon: A genome-guided transcriptome assembler using sparse flow decomposition.

High throughput sequencing of RNA (RNA-Seq) has become a staple in modern molecular biology, with applications not only in quantifying gene expression but also in isoform-level analysis of the RNA transcripts. To enable such an isoform-level analysis, a transcriptome assembly algorithm is utilized t...

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Bibliographic Details
Main Authors: Shunfu Mao, Lior Pachter, David Tse, Sreeram Kannan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232946