Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress.

The intraerythrocytic malaria parasite is susceptible to oxidative stress and this may play a role in the mechanism of action of some antimalarial agents. Here we show that exposure of the intraerythrocytic malaria parasite to the oxidising agent hydrogen peroxide results in a fall in the intracellu...

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Bibliographic Details
Main Authors: Donelly A van Schalkwyk, Kevin J Saliba, Giancarlo A Biagini, Patrick G Bray, Kiaran Kirk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594203?pdf=render