Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs

Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs

Abstract We present pandora, a novel pan-genome graph structure and algorithms for identifying variants across the full bacterial pan-genome. As much bacterial adaptability hinges on the accessory genome, methods which analyze SNPs in just the core genome have unsatisfactory limitations. Pandora app...

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Bibliographic Details
Main Authors: Rachel M. Colquhoun, Michael B. Hall, Leandro Lima, Leah W. Roberts, Kerri M. Malone, Martin Hunt, Brice Letcher, Jane Hawkey, Sophie George, Louise Pankhurst, Zamin Iqbal
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genome Biology
Subjects:
Pan-genome
Genome graph
Accessory genome
Nanopore
Online Access:https://doi.org/10.1186/s13059-021-02473-1

Internet

https://doi.org/10.1186/s13059-021-02473-1

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