Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model

Tumour angiogenesis has long been a focus of anti-cancer therapy; however, anti-angiogenic cancer treatment strategies have had limited clinical success. Tumour-associated myeloid cells are believed to play a role in the resistance of cancer towards anti-angiogenesis therapy, but the mechanisms by w...

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Bibliographic Details
Main Authors: Denver D. Britto, Barbara Wyroba, Wenxuan Chen, Rhoswen A. Lockwood, Khanh B. Tran, Peter R. Shepherd, Christopher J. Hall, Kathryn E. Crosier, Philip S. Crosier, Jonathan W. Astin
Format: Article
Language:English
Published: The Company of Biologists 2018-12-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/12/dmm035998