24 hours in the life of HIV-1 in a T cell line.

HIV-1 infects CD4+ T cells and completes its replication cycle in approximately 24 hours. We employed repeated measurements in a standardized cell system and rigorous mathematical modeling to characterize the emergence of the viral replication intermediates and their impact on the cellular transcrip...

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Bibliographic Details
Main Authors: Pejman Mohammadi, Sébastien Desfarges, István Bartha, Beda Joos, Nadine Zangger, Miguel Muñoz, Huldrych F Günthard, Niko Beerenwinkel, Amalio Telenti, Angela Ciuffi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3561177?pdf=render