A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

In Northern European descended populations, genetic susceptibility for multiple sclerosis (MS) is associated with alleles of the human leukocyte antigen (HLA) Class II gene DRB1. Whether other major histocompatibility complex (MHC) genes contribute to MS susceptibility is controversial.A case contro...

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Bibliographic Details
Main Authors: Bruce A C Cree, John D Rioux, Jacob L McCauley, Pierre-Antoine F D Gourraud, Philippe Goyette, Joseph McElroy, Philip De Jager, Adam Santaniello, Timothy J Vyse, Peter K Gregersen, Daniel Mirel, David A Hafler, Jonathan L Haines, Margaret A Pericak-Vance, Alastair Compston, Stephen J Sawcer, Jorge R Oksenberg, Stephen L Hauser, IMAGEN, IMSGC
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2892470?pdf=render

Internet

http://europepmc.org/articles/PMC2892470?pdf=render

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