Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background.

The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is universal for the studied pathogen; it has seldom bee...

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Bibliographic Details
Main Authors: Saskia Decuypere, Manu Vanaerschot, Kirstyn Brunker, Hideo Imamura, Sylke Müller, Basudha Khanal, Suman Rijal, Jean-Claude Dujardin, Graham H Coombs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22389733/?tool=EBI