A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466

In recent years, there has been a revival of interest in phenotypic-based drug discovery (PDD) due to target-based drug discovery (TDD) falling below expectations. Both PDD and TDD have their unique advantages and should be used as complementary methods in drug discovery. The PhenoTarget approach co...

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Bibliographic Details
Main Authors: Yan Xie, Yunjiang Feng, Angela Di Capua, Tin Mak, Garry W. Buchko, Peter J. Myler, Miaomiao Liu, Ronald J. Quinn
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/18/3/149