Meta-Analyses of Splicing and Expression Quantitative Trait Loci Identified Susceptibility Genes of Glioma

Meta-Analyses of Splicing and Expression Quantitative Trait Loci Identified Susceptibility Genes of Glioma

BackgroundThe functions of most glioma risk alleles are unknown. Very few studies had evaluated expression quantitative trait loci (eQTL), and insights of susceptibility genes were limited due to scarcity of available brain tissues. Moreover, no prior study had examined the effect of glioma risk all...

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Bibliographic Details
Main Authors: C. Pawan K. Patro, Darryl Nousome, The Glioma International Case Control Study (GICC), Rose K. Lai, Elizabeth B. Claus, Dora Il’yasova, Joellen Schildkraut, Jill S. Barnholtz-Sloan, Sara H. Olson, Jonine L. Bernstein, Christoffer Johansen, Robert B. Jenkins, Beatrice S. Melin, Margaret R. Wrensch, Richard S. Houlston, Melissa L. Bondy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
glioma
quantitative trait loci
eQTL
SQTL
summary data based mendelian randomization analyses
GWAS
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.609657/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.609657/full

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