The PPE domain of PPE17 is responsible for its surface localization and can be used to express heterologous proteins on the mycobacterial surface.

PPE represent a peculiar family of mycobacterial proteins characterized by a 180 aminoacids conserved N-terminal domain. Several PPE genes are co-transcribed with a gene encoding for a protein belonging to another family of mycobacterial specific proteins named PE. Only one PE-PPE couple has been ex...

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Bibliographic Details
Main Authors: Valentina Donà, Marcello Ventura, Michela Sali, Alessandro Cascioferro, Roberta Provvedi, Giorgio Palù, Giovanni Delogu, Riccardo Manganelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23469198/?tool=EBI