Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria.

Clostridium difficile causes antibiotic-associated diarrhea and pseudomembranous colitis by production of the Rho GTPase-glucosylating toxins A and B. Recently emerging hypervirulent Clostridium difficile strains additionally produce the binary ADP-ribosyltransferase toxin CDT (Clostridium difficile...

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Bibliographic Details
Main Authors: Carsten Schwan, Bärbel Stecher, Tina Tzivelekidis, Marco van Ham, Manfred Rohde, Wolf-Dietrich Hardt, Jürgen Wehland, Klaus Aktories
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2757728?pdf=render