Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas.

Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas.

Orthobunyaviruses such as Cache Valley virus (CVV) and Kairi virus (KRIV) are important animal pathogens. Periodic outbreaks of CVV have resulted in the significant loss of lambs on North American farms, whilst KRIV has mainly been detected in South and Central America with little overlap in geograp...

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Bibliographic Details
Main Authors: James I Dunlop, Agnieszka M Szemiel, Aitor Navarro, Gavin S Wilkie, Lily Tong, Sejal Modha, Daniel Mair, Vattipally B Sreenu, Ana Da Silva Filipe, Ping Li, Yan-Jang S Huang, Benjamin Brennan, Joseph Hughes, Dana L Vanlandingham, Stephen Higgs, Richard M Elliott, Alain Kohl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006884

Internet

https://doi.org/10.1371/journal.pntd.0006884

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