Immunological Drivers in Graves' Disease: NK Cells as a Master Switcher

Immunological Drivers in Graves' Disease: NK Cells as a Master Switcher

Graves' disease (GD) is a common autoimmune cause of hyperthyroidism, which is eventually related to the generation of IgG antibodies stimulating the thyrotropin receptor. Clinical manifestations of the disease reflect hyperstimulation of the gland, causing thyrocyte hyperplasia (goiter) and ex...

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Bibliographic Details
Main Authors: Daniela Gallo, Eliana Piantanida, Matteo Gallazzi, Luigi Bartalena, Maria Laura Tanda, Antonino Bruno, Lorenzo Mortara
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
natural killer cells
Graves' disease
autoimmunity
hyperthyroidism
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00406/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00406/full

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